Diabetes is a chronic metabolic disease that affects over 500 million people worldwide, who also suffer from its complications such as vascular and neuropathic disorders.

There are over 500 million people with diabetes globally, and approximately 18 million are at risk of developing 'Diabetic Foot Ulcers' each year. Remarkably, up to 34% of individuals with diabetes may experience DFU during their lifetime. Remarkably, up to 34% of individuals with diabetes may experience DFU during their lifetime.

The etiology of Diabetic Foot Ulcers (DFU) is inseparable from the complications of diabetes, mainly related to three major causes: neuropathy, peripheral arterial disease, and uneven stress on the feet.

"Why do small foot wounds become so difficult to heal, even developing into ulcers that may require amputation?" This is a question that puzzles many diabetic patients, and the key factor lies in "chronic inflammation".