The management of Diabetic Foot Ulcers (DFU) fundamentally includes three main treatment principles: wound care, offloading, and education. Patients with diabetes, whether they have a DFU or not, should constantly prevent the occurrence or worsening of ulcerative wounds, especially those with risk factors.

The severe complications of Diabetic Foot Ulcers (DFU) are a health issue that requires special attention. Effective care involves not only the healing of the wound but also the maintenance of the patient's overall health. Wound care has three key elements: debridement, off-loading, and wound dressings.

Previous studies have shown that "malnutrition" and "underweight" are common problems in patients with diabetic foot ulcers (DFUs), and may be related to the worsening of wounds and even an increase in mortality rates. Besides the core DFU treatments like surgery and wound care, whether daily diet and nutritional supplements can also help in the repair of DFU wounds is a common question among patients with diabetes.

Surgery is an invasive treatment and can be considered the most direct way to deal with a lesion, ranging from minor wound debridement to major limb amputation. Although surgery is usually considered when symptoms are severe or conservative treatment is ineffective, appropriate surgery when necessary can delay the progression of the disease and prevent serious complications.

The non-surgical treatment for diabetic foot ulcers (DFUs) involving various medications and therapies. However, due to varying levels of evidence, this article will only introduce few common treatment methods and some alternative therapies. Professional medical advice should be sought when applying these treatments in practice.